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2018, 03, v.40;No.182 207-210
溶菌酶的研究进展及应用
基金项目(Foundation): 青岛大学医学部“临床医学+X”工程科研项目(2017M39);青岛大学基础医学院大学生创新创业训练“海洋溶菌酶滴眼液对鼠真菌性角膜炎的实验研究”资助
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发布时间: 2018-07-02
出版时间: 2018-07-02
网络发布时间: 2018-07-02
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摘要:

<正>溶菌酶(Lysozyme)又称胞壁质酶(Muramidase),广泛存在于自然界,具有抗细菌、真菌及肿瘤等多种药理作用,具有生物相容性好对组织无刺激性、无毒性的特点,已被制作为一种性质优良杀伤病原微生物而不破坏机体的酶制剂。根据其分子结构和来源的不同分为6类:植物溶菌酶、微生物溶菌酶、噬菌体溶菌酶(主要为T4噬菌体)、C型(蛋清溶菌酶、胃溶菌酶等)、G型(鹅型溶菌酶)和I型(无

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参考文献

[1]Liu YY,Wang Y,Walsh TR,et al.Emergence of plasmid-mediated colistin resistance mechanism MCR-1in animals and human beings in China:a microbiological and molecular biological study[J].Lancet Infect Dis,2016,16(2):161-168.

[2]Sherman EX,Hufnagel DA,Weiss DS.MCR-1confers cross-resistance to lysozyme[J].Lancet Infect Dis,2016,16(11):1226-1227.

[3]Sowa-Jasilek A,Zdybicka-Barabas A,Staczek S,et al.Galleria mellonella lysozyme induces apoptotic changes in Candida albicans cells[J].Microbiol Res,2016,193(10):121-131.

[4]Smedowski A,Tarnawska D,Orski M,et al.Cytoarchitecture of epithelial inflammatory infiltration indicates the aetiology of infectious keratitis[J].Acta Ophthalmol,2017,95(4):405-413.

[5]Lee W,Ku SK,Na DH,et al.Anti-Inflammatory Effects of Lysozyme Against HMGB1in Human Endothelial Cells and in Mice[J].Inflammation,2015,38(5):1911-1924.

[6]Sawasdipuksa N,Lei ZT,Sumner LW,et al.A Lysozyme with Antifungal Activity from Pithecellobium dulce Seeds[J].Food Technology and Biotechnology,2011,49(4):489-494.

[7]Ajesh K,Sreejith K.A Novel Antifungal Protein with Lysozyme-Like Activity from Seeds of Clitoria ternatea[J].Applied Biochemistry and Biotechnology,2014,173(3):682-693.

[8]Ly-Chatain MH,Moussaoui S,Vera A,et al.Antiviral effect of cationic compounds on bacteriophages[J].Front Microbiol,2013,4(3):46.

[9]Mahanta S,Paul S,Srivastava A,et al.Stable self-assembled nanostructured hen egg white lysozyme exhibits strong anti-proliferative activity against breast cancer cells[J].Colloids and Surfaces B-Biointerfaces,2015,130(1):237-245.

[10]Wu T,Zhang W,Yang G,et al.HMGB1overexpression as a prognostic factor for survival in cancer:a meta-analysis and systematic review[J].Oncotarget,2016,7(31):50417-27.

[11]Ernest V,Gajalakshmi S,Mukherjee A,et al.Enhanced activity of lysozyme-AgNP conjugate with synergic antibacterial effect without damaging the catalytic site of lysozyme[J].Artif Cells Nanomed Biotechnol,2014,42(5):336-343.

[12]Hashemi MM,Aminlari M,Forouzan MM,et al.Production and Application of Lysozyme-Gum Arabic Conjugate in Mayonnaise as a Natural Preservative and Emulsifier[J].Polish Journal of Food&Nutrition Sciences,2018,68(1):33-44.

[13]Jiang S,Yang Q,Jie Y,et al.Enhanced antibacterial activity of lysozyme immobilized on chitin nanowhiskers[J].Food Chemistry,2017,221(8):1507-1513.

[14]Li XM,Wang XY,Gao XJ.Synergistic effects of lysozyme with EDTA-2Na on antibacterial activity][J].Journal of Peking University(Health Sciences),2015,47(1):52.

[15]Feng K,Wen P,Yang H,et al.Enhancement of the antimicrobial activity of cinnamon essential oil-loaded electrospun nanofilm by the incorporation of lysozyme[J].Rsc Advances,2017,7(3):1572-1580.

[16]Ladan A,Marjan Mohammadi H,Mahmoud A.Modified Lysozymes as Novel Broad Spectrum Natural Antimicrobial Agents in Foods[J].Journal of Food Science,2014,79(6):R1077.

[17]宋文君,曹巧玲.康复新液超声雾化吸入辅治小儿疱疹性咽峡炎疗效观察[J].医药前沿,2013,35(11):140-141.

[18]张杰.海洋溶菌酶复合保鲜剂抑菌效果的研究[J].河北渔业,2014,42(8):5-7.

[19]Cooper CA,Garas Klobas LC,Maga EA,et al.Consuming transgenic goats'milk containing the antimicrobial protein lysozyme helps resolve diarrhea in young pigs[J].PLoS One,2013,8(3):e58409.

[20]Satish L,Rana S,Arakha M,et al.Impact of imidazolium-based ionic liquids on the structure and stability of lysozyme[J].Spectroscopy Letters,2016,49(6):383-390.

基本信息:

中图分类号:R977.3

引用信息:

[1]朱元镇,刘婧仪,于常红.溶菌酶的研究进展及应用[J].山东医学高等专科学校学报,2018,40(03):207-210.

基金信息:

青岛大学医学部“临床医学+X”工程科研项目(2017M39);青岛大学基础医学院大学生创新创业训练“海洋溶菌酶滴眼液对鼠真菌性角膜炎的实验研究”资助

发布时间:

2018-07-02

出版时间:

2018-07-02

网络发布时间:

2018-07-02

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